| UK | Opp | OTs | Date | School | Place | Event | All-Time |
| 77 | 51 | | 11/4/2025 | Nicholls | Lexington | BBN United Tipoff Classic | 1-0 |
| 107 | 59 | | 11/7/2025 | Valparaiso | Lexington | BBN United Tipoff Classic | 3-0 |
| 88 | 96 | | 11/11/2025 | Louisville | Louisville | | 40-18 |
| 99 | 53 | | 11/14/2025 | Eastern Illinois | Lexington | BBN United Tipoff Classic | 1-0 |
| 66 | 83 | | 11/18/2025 | Michigan State | New York | Champions Classic | 14-13 |
| 88 | 46 | | 11/21/2025 | Loyola (MD) | Lexington | | 2-0 |
| 104 | 54 | | 11/26/2025 | Tennessee Tech | Lexington | | 6-0 |
| 64 | 67 | | 12/2/2025 | North Carolina | Lexington | ACC/SEC Challenge | 18-26 |
| 59 | 94 | | 12/5/2025 | Gonzaga | Nashville | | 2-3 |
| 103 | 67 | | 12/9/2025 | North Carolina - Central | Lexington | | 1-0 |
| 72 | 60 | | 12/13/2025 | Indiana | Lexington | | 33-25 |
| 78 | 66 | | 12/20/2025 | St. John's | Atlanta | CBS Sports Classic | 12-5 |
| 99 | 85 | | 12/23/2025 | Bellarmine | Lexington | | 2-0 |
| 74 | 89 | | 1/3/2026 | Alabama | Tuscaloosa | | 117-45 |
| 68 | 73 | | 1/7/2026 | Missouri | Lexington | | 16-4 |
| 92 | 68 | | 1/10/2026 | Mississippi State | Lexington | | 105-21 |
| 75 | 74 | | 1/13/2026 | LSU | Baton Rouge | | 95-29 |
| 80 | 78 | | 1/17/2026 | Tennessee | Knoxville | | 164-79 |
| 85 | 80 | | 1/21/2026 | Texas | Lexington | | 3-1 |
| 72 | 63 | | 1/24/2026 | Ole Miss | Lexington | | 112-15 |
| 55 | 80 | | 1/27/2026 | Vanderbilt | Nashville | | 158-51 |
| 85 | 77 | | 1/31/2026 | Arkansas | Fayetteville | | 37-15 |
| 94 | 78 | | 2/4/2026 | Oklahoma | Lexington | | 6-0 |
| 74 | 71 | | 2/7/2026 | Tennessee | Lexington | | 165-79 |
| 83 | 92 | | 2/14/2026 | Florida | Gainesville | | 111-43 |
| 78 | 86 | | 2/17/2026 | Georgia | Lexington | | 132-30 |
| | | 2/21/2026 | Auburn | Auburn | | 98-24 |
| | | 2/24/2026 | South Carolina | Columbia, SC | | 55-15 |
| | | 2/28/2026 | Vanderbilt | Lexington | | 158-51 |
| | | 3/3/2026 | Texas A & M | College Station | | 14-6 |
| | | 3/7/2026 | Florida | Lexington | | 111-43 |